Measles Outbreak 2026

If you have a rash or fever and are not vaccinated against measles, please schedule a virtual visit.

Convenient, High-Quality Urgent Care on Harbison Blvd in Columbia

Our patients are our priority at Prisma Health Urgent Care, and we are passionate about providing fast and reliable medical care on Harbison Boulevard in Columbia, SC. When you step into our clinic, we hope you immediately feel valued, heard, and cared for. Our goals are to proactively serve you and empower you to take control of your health so you can continue to thrive.


We are a walk-in clinic, but you can also book ahead or schedule a virtual visit with our certified medical professionals to get the help you need when you need it.

Serving Columbia • Irmo • Walden • Seven Oaks • Yacht Cove • St. Andrews

Urgent Care Close to Home

Whether you're shopping at Columbiana Centre or commuting along Harbison Boulevard, we’re easily accessible for your healthcare needs.


We’re conveniently located in the heart of Harbison, just minutes from I-26. You can find us between Nothing Bundt Cakes and the Goodyear Auto Service Center across from Target.

Maps & Directions

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Getting Here

From 1-26:

  • Take exit 103 for Harbison Boulevard.

  • Continue on Harbison Boulevard for about 1.5 miles.

  • You’ll find our clinic on your right as you pass Taco Bell.


From the North West via US-176/Broad River Road:

  • Follow US-176/Broad River Road until you reach Woodrow Street.

  • Continue on Woodrow Street for about 1.4 miles. Then, turn right on Thames Valley Road, followed by an immediate left onto St. Andrews Road.

  • Continue on St. Andrews Road for about 1.9 miles, passing by a McDonald’s on your right.

  • Turn left onto Harbison Boulevard, and our clinic will be on your left.


When you arrive, there are ample parking spots in the plaza where our clinic is located.

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Serving Nearby Communities

Our clinic proudly serves patients from Columbia, Irmo, Walden, Seven Oaks, Yacht Cove, and St. Andrews, providing easy access to expert care in the Midlands and surrounding areas.

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Outstanding Care for All

Residents of Columbia and nearby areas deserve outstanding, responsive urgent care services that enhance and support their primary care. At Prisma Health Urgent Care, you can expect that and more. We’re committed to helping you lead your healthiest and best life.

Thousands of 5-star reviews

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★★★★★
☆☆☆☆☆

Very friendly staff. I did not have to wait long at all to be seen by the doctor. Doctor was very thorough and explained everything that she was doing. Definitely a pleasant experience

Greer

Very friendly staff. I did not have to wait long at all to be seen by the doctor. Doctor was very thorough and explained everything that she was doing. Definitely a pleasant experience

Greer

Excellent, everyone working there was very friendly and helpful. Super appreciate you all working to help other people out!

Verdae

Everyone was very nice and helpful and took very good care of me, I am so glad to have them near me

Taylors

Just 2 min waiting time and a super friendly and knowledgable physician! Thanks for the great service!

Greenville - Woodruff Rd.

I checked in online this morning. Went to my appointment time and was seen right away. Spoke to the doctor. Explain my concerns. Got an x-ray done and results. Was out the door less than 45 minutes. Great staff very friendly. I would recommend them

Greer

Friendly service! True to appointment time! Quick to test for everything that was possible with the symptoms present. Definitely recommend going here!

Anderson

Receive Best-in-Class Urgent Care Services

Prisma Health Urgent Care is setting the new standard of urgent care in Columbia by providing fast, convenient, and high-quality treatments for non-life-threatening injuries and illnesses. From flu care and minor sprains to X-rays, select vaccines, diagnostic services, and more, our certified providers are here to ensure you get the right care, right away in a facility that meets the highest standards of cleanliness and efficiency.


Our clinic on Harbison Boulevard is open from 8 a.m. to 8 p.m., Monday through Sunday, for all your urgent care needs. We always accept walk-ins, and you can reserve your spot online or schedule a virtual visit whenever you need same-day service.

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Comprehensive Care & Services

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Digital X-ray

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Lab

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EKG

Top Notch Care & Convenient Services

Illness
  • Colds
  • Influenza (flu)
  • Strep/sore throat
Injuries
  • Acute fracture (non-displaced)
  • Minor concussions
  • Back pain or strains
Testing & Vaccines
  • Diagnostic Testing
  • Physical Exams
  • Vaccinations