Walk-In Urgent Care in Mauldin, SC on South Main Street

For fast, dependable urgent care in Mauldin, Prisma Health Urgent Care offers same-day testing and treatment in a modern clinic with extended daily hours. Our team cares for many common illnesses and minor injuries and provides on-site testing so you can get answers in one stop. Walk in seven days a week or book ahead online to reserve your spot in line before you arrive.

PHUC AFD Seal 2026.png

Serving Mauldin, Greenville, Simpsonville, Fountain Inn

Convenient Urgent Care Near the Heart of Mauldin

Our Mauldin location makes it easy to get care without going far out of your way. Located on South Main Street, our clinic is well placed for patients coming from Mauldin, nearby Greenville, Simpsonville, and other growing communities in this part of the Upstate. When you need same-day care, our location keeps things simple.

Maps & Directions

location-image1.webp
location-image2.webp

Getting Here

From I-385:

  • Take Exit 34 for Butler Road toward Mauldin.

  • Turn left (southwest) onto Butler Road.

  • Continue approximately 2.5 miles to South Main Street (US-276).

  • Turn left onto South Main Street.

  • The clinic is near Mauldin First Baptist Church.


From Simpsonville (via US-276/Main Street):

  • Head north on US-276/Main Street toward central Mauldin.

  • Continue through town.

  • The clinic is on South Main Street, next to Publix, on the right.


There is plenty of free parking in front of the clinic.

Serving Nearby Communities.svg

Serving Nearby Communities

We’re proud to deliver quality care for patients from Mauldin, Greenville, Simpsonville, Fountain Inn, and surrounding areas.

Compassionate Care When You Need It Most.svg

Urgent Care Close to Home

Need medical care without the long wait? Walk in today or book ahead online to reserve your spot in line at our Mauldin clinic.

Thousands of 5-star reviews

Prisma Health Urgent Care Reviews
★★★★★
☆☆☆☆☆

Very friendly staff. I did not have to wait long at all to be seen by the doctor. Doctor was very thorough and explained everything that she was doing. Definitely a pleasant experience

Greer

Very friendly staff. I did not have to wait long at all to be seen by the doctor. Doctor was very thorough and explained everything that she was doing. Definitely a pleasant experience

Greer

Excellent, everyone working there was very friendly and helpful. Super appreciate you all working to help other people out!

Verdae

Everyone was very nice and helpful and took very good care of me, I am so glad to have them near me

Taylors

Just 2 min waiting time and a super friendly and knowledgable physician! Thanks for the great service!

Greenville - Woodruff Rd.

I checked in online this morning. Went to my appointment time and was seen right away. Spoke to the doctor. Explain my concerns. Got an x-ray done and results. Was out the door less than 45 minutes. Great staff very friendly. I would recommend them

Greer

Friendly service! True to appointment time! Quick to test for everything that was possible with the symptoms present. Definitely recommend going here!

Anderson

Comprehensive Urgent Care in Mauldin With Prisma Health

At our Mauldin clinic, we treat a broad range of non-life-threatening injuries and illnesses in children, teens, and adults. We also offer helpful on-site services such as diagnostic testing, digital X-rays, physical exams, and select vaccines, all in one convenient setting. Whether you are dealing with a seasonal illness, a minor injury, or a last-minute health need, our team is ready to provide attentive care that helps you move forward faster.


Walk in today or book ahead online to reserve your appointment.

location-image4.webp

Comprehensive Care & Services

Service Digital X ray

Digital X-ray

Services Labs

Lab

Service ekg

EKG

Top Notch Care & Convenient Services

Injuries
  • Bone & Joint Injuries
  • Hand, Foot, & Nail Injuries
  • Skin & Surface Wounds
Testing & Vaccines